Study protocol for assessment of the coagulation potential of concomitantly used factor VIII concentrates in patients with haemophilia A with emicizumab prophylaxis (CAGUYAMA Study): a multicentre open-label non-randomised clinical trialMasahiro Takeyama, Naoki Ozu, Shu Kasama, Masato Kasahara, Masanori Matsumoto, Midori Shima, Keiji Nogami
10 July 2023
Low-dose intravenous immunoglobulin for children with newly diagnosed immune thrombocytopenia: protocol of a systematic review and meta-analysisXiangge Ren, Miaomiao Zhang, Xiaohan Zhang, Peidong Zhao, Wensheng Zhai
29 June 2023
DosEmi study protocol: a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia AAnouk Donners, Konrad van der Zwet, Antoine C G Egberts, Karin Fijnvandraat, Ron Mathôt, Ilmar Kruis, Marjon H Cnossen, Roger Schutgens, Rolf T Urbanus, Kathelijn Fischer
26 June 2023
ALL-RIC trial protocol: a comparison of reduced dose total body irradiation (TBI) and cyclophosphamide with fludarabine and melphalan reduced intensity conditioning in adults with acute lymphoblastic leukaemia (ALL) in complete remissionDavid I Marks, Anna Castleton, Eduardo Olavarria, Maria Gilleece, Adele Fielding, George Mikhaeel, Matthew Beasley, Patricia Diez, Aimee Jackson, Andrea Hodgkinson, Mohamed Elhanied, Ronjon Chakraverty
1 June 2023
Effect of cognitive–behavioural therapy on resilience and relapse in adult patients with substance use disorder: a systematic review protocolIbraheem Mhaidat, Mohammad Reza Taherian, Seyed Saeed Hashemi Nazari, Alireza Mosavi-Jarrahi, Haniye Yeganeh, Nabeel Al-Yateem, Amina M Al Marzouqi, Syed Azizur Rahman
12 May 2023
Faecal microbiota transplantation to prevent complications after allogeneic stem cell transplantation for haematological malignancies: a study protocol for a randomised controlled phase-II trial (the FMT-allo study)Aurore Dougé, Aurélie Ravinet, Alexandrine Corriger, Aurélie Cabrespine, Mathieu Wasiak, Bruno Pereira, Harry Sokol, Stéphanie Nguyen, Jacques-Olivier Bay
2 May 2023
Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I–II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21)Hirotoshi Sakaguchi, Katsustugu Umeda, Itaru Kato, Kimiyoshi Sakaguchi, Hidefumi Hiramatsu, Hiroyuki Ishida, Hiromasa Yabe, Hiroaki Goto, Yuta Kawahara, Yuka Iijima Yamashita, Masashi Sanada, Takao Deguchi, Yoshiyuki Takahashi, Akiko Saito, Hisashi NomaSee the full list of authors
17 April 2023
Efficacy and safety of novel oral anticoagulants for the treatment of cancer-associated venous thromboembolism: protocol for an umbrella review of systematic reviews and meta-analysesYunqing Xia, Liang Tang, Yu Hu
6 April 2023
The Pyruvate Kinase Deficiency Global Longitudinal (Peak) Registry: rationale and study designRachael F Grace, Eduard J van Beers, Joan-Lluis Vives Corrons, Bertil Glader, Andreas Glenthøj, Hitoshi Kanno, Kevin H M Kuo, Carl Lander, D Mark Layton, Dagmar Pospíŝilová, Vip Viprakasit, Junlong Li, Yan Yan, Audra N Boscoe, Chris BowdenSee the full list of authors
23 March 2023
Psychometric evaluation of the NTDT-PRO questionnaire for assessing symptoms in patients with non-transfusion-dependent beta-thalassaemiaAli T Taher, Khaled M Musallam, Vip Viprakasit, Antonis Kattamis, Jennifer Lord-Bessen, Aylin Yucel, Shien Guo, Christopher Pelligra, Alan L Shields, Jeevan K Shetty, Dimana Miteva, Luciana Moro Bueno, Maria Domenica Cappellini
22 March 2023